What Is Ketamine Therapy? Full Guide On Results, Process, And Cost

  • Jacob J. Bentley
  • April 10, 2025
Ketamine Therapy

When nothing seems to work, dealing with depression or anxiety gets even harder. It drains your energy and makes everyday life tough. That’s the reality for many living with depression, anxiety, or past trauma. Ketamine Therapy has started to shift that experience for people.

It offers something different, something that feels like a break. It’s not a miracle cure. But for some, it brings relief where nothing else could. It works fast, gentle, and deeply personal.

In this blog, you’ll find clear answers about what ketamine does and how long it stays. Also, what it feels like and what to expect when it comes to cost and coverage.

What is Ketamine Therapy?

Ketamine therapy uses small doses of ketamine to help with mental health issues. This includes depression, anxiety, or PTSD that doesn’t respond to regular treatments. Usually, ketamine works as an anesthetic. But at low doses, it acts differently in the brain.

Ketamine affects a brain chemical called glutamate. And it helps you build new thought patterns quickly. It works fast. Some people start feeling better just hours after taking it. But doctors prescribe it "off-label." This means it’s not FDA-approved for mental health yet.

How Long Does Ketamine Stay in Your System?

Ketamine stays in your body longer than you might think. In adults, ketamine has a half-life of around 2.5 to 3 hours. Half-life simply means the real amount is reduced to half.

When ketamine levels start going down, you might feel a mood shift. Some people take another dose to avoid this feeling. But doing this is risky. It can lead to addiction or serious health problems.

There are various tests that can check ketamine in your body. And all of them give different results.

  • Blood tests can usually detect ketamine up to about 24 hours after taking it.
  • In saliva tests, ketamine can show up for roughly 3 days.
  • Urine tests can pick it up even 30 days after your last dose.
  • And hair tests? Those can detect ketamine use for up to 90 days.

How Long Does Ketamine Pain Relief Last?

Ketamine wasn’t always known for treating depression or pain. Doctors first used it as a surgical anesthetic. It interacts differently with your brain to reduce pain. And that makes ketamine a good option for pain management.

You might wonder how long ketamine therapy will relieve your pain. The truth is, it’s different for everyone. Some people feel relief right after their first session. Others might need several treatments before noticing real improvement.

A few factors affect how well ketamine eases your pain.

  • Your pain intensity. Severe pain usually requires more sessions to achieve lasting results.
  • How often you get treatments is another factor. Some people find lasting relief after one round. But others may need more treatments.
  • Your own brain chemistry plays a big role, too. It affects how effectively ketamine works for you personally.

Does Ketamine Therapy Get You High?

Prior to your therapy, an expert carefully manages your dose. It can help minimize any side effects. And when you receive the infusion, your mind may enter a different state. That's why you should get the treatment from a medical professional.

Initially, you might not feel anything unusual. But as the infusion goes on, you start noticing its effects.

  • You might feel lighter, almost like you're floating.
  • Some people say it feels like a heavy burden is lifted away.
  • You may also feel a deep sense of calm and relaxation.

Sometimes, ketamine can even make you see colors, shapes, or images. These visuals are not the same for all. Everyone reacts differently to ketamine. It makes each person's experience unique and very personal.

Once the infusion stops, the sensations gently fade, bringing you back gradually.

ketamine therapy

How Much Does Ketamine Therapy Cost?

Ketamine therapy can be expensive. In most cases, prices vary between clinics. You might have to pay around $400 to $800 for just one session.

Usually, you have to take multiple sessions to get better, lasting results. This is the case for most people. This means a full therapy treatment can cost from $3,000 to $6,000. In some cases even more.

IV infusions usually cost more. But it has a lasting and quick effect compared to oral or nasal treatments. Many clinics offer discounts to help make it affordable. But they are not available all the time. You can ask your clinic for a detailed price list. Review this list before you start any treatment. This helps you plan your budget and avoid surprise expenses later.

Does Insurance Cover Ketamine Therapy?

Most insurance companies still don't fully cover ketamine therapy. They consider it experimental for mental health or pain management. But in certain situations, you might get partial coverage. Always speak with your insurance provider before booking a session. Ask if they cover ketamine treatment for depression, PTSD, or chronic pain.

Some clinics will even help you submit insurance claims for possible refunds. Checking coverage first is smarter than paying fully out-of-pocket later. Confirm exactly what's included and what's not before starting treatment. This gives you peace of mind and prevents unexpected bills.

Manage Ketamine Therapy Cost With Credee

There’s no doubt that ketamine therapy is costly. And the fact insurance won’t cover it is a big issue. It can give you second thoughts about choosing the treatment. Or worse, adding more stress to your life.

But you might get flexible payment options from some clinics. If they are using platforms like Credee to provide payment flexibility. You can inquire about these payment options during consultations. This way, you can manage therapy costs and get the required session.

The End Note

Ketamine Therapy isn’t for everyone. But for many, it has opened a door for healing. This therapy is not just about the science or the sessions. It’s about you finding a space to feel better.

Before taking ketamine for anxiety or something else, talk to professionals you trust and clear your doubts. Also, look into payment flexibility if cost feels like a barrier. Relief might come slowly after the treatment, but it’s okay to seek it in new ways.

Worried About Ketamine Therapy Costs?

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FAQs

1. How Many Ketamine Treatments for Depression Are Mandatory?

There’s no fixed number that works for everyone. Most people begin with a short series—about 6 sessions over 2-3 weeks. After that, follow-up treatments are based on how you respond. It’s all about finding what your mind needs to heal.

2. Who Is Not a Good Candidate for Ketamine Therapy?

If you have high blood pressure or a history of active substance abuse, ketamine therapy might not be safe for you. Talk openly with your doctor about your full health background.

3. Is Ketamine Infusion Covered by Insurance?

In most cases, no. But depending on your plan and medical history, partial coverage might be possible. Always double-check first.

4. How Much Is Ketamine Therapy?

Prices differ by clinic and treatment type. IV infusions usually cost more than oral options. And since multiple sessions are needed, the total can add up. Some clinics offer packages or payment plans to ease the load.

5. Is Ketamine Therapy Covered by Insurance?

Coverage is still limited. Ketamine isn’t FDA-approved for mental health yet, so many plans exclude it. But don’t lose hope—some insurers are starting to reconsider, especially for treatment-resistant conditions. It’s worth asking.

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